BIRMINGHAM, AL (REIT Media) March 14, 2008 - Medical Properties Trust, Inc. (the “Company”) (NYSE: MPW), announced today that it has entered into a definitive purchase and sale agreement to acquire a portfolio of up to 21 healthcare facilities across 15 states from HCP, Inc. (NYSE:HCP) for an aggregate purchase price of approximately $371 million. Subject to customary closing conditions, the Company expects to complete the acquisition in stages beginning March 28, 2008 through the end of the second quarter of 2008.

“This portfolio acquisition is a transformative event for MPT,” said Edward K. Aldag Jr., chairman and president and CEO. “The portfolio will increase the number of properties in our portfolio by 75%, substantially increase our tenant diversification with eight new, well-known operators whom we believe to be of high quality, as well as significantly improve our geographic footprint.”

The portfolio to be acquired from HCP consists of:

• 7 acute care hospitals in five states;
• 5 inpatient rehabilitation hospitals in five states;
• 3 long-term acute care hospitals in three states; and
• 6 wellness centers in three states.

Based on December 2007 rent, the HCP properties would have generated approximately $33.4 million of annualized cash rent in 2007. Following the acquisitions, the Company expects to report revenue from the properties on a GAAP, or straight-line, basis. The properties are currently subject to 14 separate leases, which will be assumed by the Company. The leases expire between 2009 and 2027, plus renewal options. All of the properties are subject to cross-defaults, master leases, parent guarantees or individual guarantees.

More than half of the properties are subject to certain preemptive purchase rights or purchase options held by existing tenants. While the Company does not currently believe that a material amount of these rights will be exercised, the notice and option period associated with these rights may delay the Company’s purchase of the applicable properties and, if exercised, the rights would prevent the Company’s purchase of these properties.

The Company intends to fund the acquisition of the HCP properties with proceeds from the sales of a combination of common stock and debt securities, the net proceeds the Company receives from its previously announced purchase and sale transactions with Vibra Healthcare, LLC, and borrowings under its existing credit facilities. The Company has also secured commitments from a syndicate of lenders for a senior secured interim loan facility, which is expected to provide up to $300.0 million of any unfunded balance of the purchase price.

About Medical Properties Trust, Inc.

Medical Properties Trust, Inc. is a Birmingham, Alabama based self-advised real estate investment trust formed to capitalize on the changing trends in healthcare delivery by acquiring and developing net-leased healthcare facilities. These facilities include inpatient rehabilitation hospitals, long-term acute care hospitals, regional acute care hospitals, ambulatory surgery centers and other single-discipline healthcare facilities, such as heart hospitals, orthopedic hospitals and cancer centers.

The statements in this press release that are forward looking are based on current expectations and actual results or future events may differ materially. Words such as "expects," "believes," "anticipates," "intends," "will," "should" and variations of such words and similar expressions are intended to identify such forward-looking statements, which include statements including, but not limited to, consummation of the HCP acquisition and the offerings to fund the acquisition, completion of projects under development, acquisition of healthcare real estate, completion of additional debt arrangements, the capacity of the Company's tenants to meet the terms of their agreements, net income per share and FFO per share. Such forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the actual results of the Company or future events to differ materially from those express in or underlying such forward-looking statements, including without limitation: national and economic, business, real estate and other market conditions; the competitive environment in which the Company operates; the execution of the Company's business plan; financing risks; the Company's ability to attain and maintain its status as a REIT for federal income tax purposes; acquisition and development risks; potential environmental and other liabilities; and other factors affecting the real estate industry generally or the healthcare real estate in particular. For further discussion of the facts that could affect outcomes, please refer to the "Risk Factors" section of the Company's Form 10-K for the year ended December 31, 2007. Except as otherwise required by the federal securities laws, the Company undertakes no obligation to update the information in this press release.

Medical Properties Trust
Charles Lambert, Finance Director, 205-397-8897
clambert@medicalpropertiestrust.com