BIRMINGHAM, AL (REIT Media) March 14, 2008 - Medical Properties Trust, Inc. (the "Company") (NYSE: MPW) announced today that its operating partnership, MPT Operating Partnership, L.P. (the "Operating Partnership"), has commenced an offering of $125.0 million aggregate principal amount of exchangeable senior notes due 2013 (the "notes") through an offering to qualified institutional buyers in reliance on Rule 144A under the Securities Act of 1933, as amended. The Operating Partnership expects to grant the initial purchasers an option to purchase up to an additional $18.75 million aggregate principal amount of notes to cover over-allotments, if any.

The notes will be exchangeable for cash up to their principal amount and shares of the Company's common stock for the remainder, if any, of the exchange value in excess of such principal amount. The notes will be senior unsecured obligations of the Operating Partnership, guaranteed by the Company. The interest rate, exchange rate and other terms of the notes will be determined by negotiations between the Company and initial purchasers of the notes.

The Company intends to use the net proceeds from the offering to fund a portion of the purchase price of its acquisition of a portfolio of up to 21 healthcare facilities across 15 states from HCP, Inc. for an aggregate purchase price of approximately $371 million. The portfolio consists of seven acute care hospitals, three long-term acute care hospitals, five inpatient rehabilitation hospitals, as well as six wellness centers. Subject to customary closing conditions, the Company expects to complete the acquisition in stages beginning March 28, 2008 through the end of the second quarter of 2008.

The Company intends to fund the remainder of the purchase price of the acquisition of the HCP properties with proceeds from the sale of common stock, the net proceeds the Company receives from its previously announced purchase and sale transactions with Vibra Healthcare, LLC, and borrowings under its existing credit facilities. The Company has also secured commitments from a syndicate of lenders for a senior secured interim loan facility, which is expected to provide up to $300.0 million of any unfunded balance of the purchase price.

This notice does not constitute an offer to sell or a solicitation of an offer to buy securities. Any offers of the securities will be made only by means of a private offering memorandum. The notes and any common stock of the Company issuable upon the exchange of the notes have not been registered under the Securities Act of 1933, as amended, or the securities laws of any other jurisdiction and may not be offered or sold absent registration or an applicable exemption from registration requirements.

The statements in this press release that are forward looking are based on current expectations and actual results or future events may differ materially. Words such as "expects," "believes," "anticipates," "intends," "will," "should” and variations of such words and similar expressions are intended to identify such forward-looking statements. Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the actual results of the Company or future events to differ materially from those expressed in or underlying such forward-looking statements, including without limitation: the Company’s ability to consummate this offering and the use of the proceeds therefrom; the Company’s ability to consummate the HCP acquisition and other acquisitions; national and economic, business, real estate and other market conditions; the competitive environment in which the Company operates; the execution of the Company's business plan; financing risks; the Company's ability to attain and maintain its status as a REIT for federal income tax purposes; acquisition and development risks; potential environmental and other liabilities; and other factors affecting the real estate industry generally or the healthcare real estate in particular. For further discussion of the facts that could affect outcomes, please refer to the "Risk factors" section of the Company's Form 10-K for the year ended December 31, 2007. Except as otherwise required by the federal securities laws, the Company undertakes no obligation to update the information in this press release.

Medical Properties Trust
Charles Lambert, Finance Director, 205-397-8897
clambert@medicalpropertiestrust.com